I just read another interesting article that stated there are sometimes as much as 10 times more mast cells in angiolipomas than there normally are in normal lipomas. Here is one the section of the article stated:
“To characterize the potential role of mast cells (MC) in angiogenesis, this study tests the hypothesis that MC may be more abundant in angiolipomas than in classic lipomas. MC counts were compared in 13 subcutaneous angiolipomas and 15 subcutaneous classic lipomas stained with Giemsa. Angiolipomas had ten times as many MC as did classic lipomas.”
That was somewhat interesting because we know that there is some involvement with mast cells and cholinergic urticaria. There were 10 times the number of mast cells in the angiolipoma, compared to regular lipomas.