There are several diseases that mimic the symptoms of cholinergic urticaria. Itching, stinging, and a prickling sensation can be associated with several disorders, including miliaria rubra, tinea versicolor, niacin flushing, and so forth.
When seeking a diagnosis, it’s a good idea to learn about some of these other disorders so that you can be more educated when explaining your symptoms to your doctor.
The video below contains information on the other diseases that mimic cholinergic urticaria:
Miliaria, Prickly Heat, and Other Diseases that Mimic Cholinergic Urticaria
Post by: Klope62 on May 05, 2008, 12:07:23 AM
For about the last 7 or so years of my life, I’ve been bothered by a weird condition.
If I got hot, excited, nervous, or basically anything evoking sweat, I would get this awful “prickle” feeling around various areas of my body. I could only compare it to the sensation of getting poked by hundreds of small needles, or getting bit by a colony of small ants.
This has bothered me for years, and I have been trying to find answers. I even made a post on another forum back in 2003. Back then, I knew that the condition “Prickly Heat”, “Miliaria” didn’t necessarily match up to what I was experiencing. Miliaria is a temporary condition, it’s more like a rash comparable to Poison Ivy, rather than a condition that sticks with you. However, I still accepted to the answer…just to have one.
I let the topic die, but as the years progressed, I was still searching for answers. Around a year ago, I discovered this topic. It was a huge relief just to know that I “wasn’t crazy”, and that there were other people out there experiencing the same thing as me. Unfortunately, as I read through the entire topic, not a single person reported that they had relief, or even identification on what the condition was. In fact, it was almost the same story for most of the people who saw a health care professional. They would go in reporting their problem, they would be prescribed weird medication that did not work, then they would eventually get described antidepressants and told “it’s all in your head”, “it’s all anxiety attacks”, etc. So, while the discovery of the topic was, and still is a huge relief, it was also like a blow at the same time.
In the past year, the problem has been increasing and getting even more violent, and I think both the inconsistent temperatures, as well as the added stress of College have contributed it to it. I’m not able to eat spicy foods, or take hot showers as long as I would like to, without the prickly sensation. It has led me to be more determined than ever to find what the heck is going on with my skin
There is no cure, and scientist are still unsure exactly why it ever starts, but there is treatment. If anti-histamine treatment does not work, reports have shown that Danazol, which is a steroid, does. I would be weary of taking a steroid, but I would hope that I would never even have to get to that point. The average onset of the disorder is about 7.5 years, I am sure I have had it for that long, if not more already. There have also been reports of cases where it has lasted for 30+ years. So it is something I could have to deal with for a big portion of my adult life.
This all being said, I have never gone to the dermatologist. Mainly because American health care sucks, and if I ever go, I except to leave with some results. Now that I have something that it could possibly be, as well as other reports, and pictures, I do plan on going to a dermatologist soon, and hopefully getting some relief, because that would be amazing.
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Title: Re: I am sure I have it.
Post by: HivesGuy on May 05, 2008, 07:30:27 AM
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Hello Klope62,
Thanks for the wonderful post & welcome to the forum!
I appreciate you sharing your story & posting the pictures. It sounds like the same thing most of us are suffering from: “cholinergic urticaria” or some type of heat related hives.
I can definitely understand your frustrations & also your relief about finding out that you aren’t the only one with this condition. Even though we may have to suffer with this for 7 years, 30 years, or even the rest of our lives, I try to stay positive. Sure, I have my moments where I get so frustrated, mad, and even depressed because of this annoying condition.
But at the same time, what if I had a deadly form of cancer? Or what if I had an even worse physical or mental condition. Even though this is hard to live with, I can’t help but be glad that I don’t have something worse. I try to be thankful for not only what I do have in my life (my wife, family, etc.), but also what I don’t have (such as a terminal disease, etc.).
Anyways, thanks again for your great post, and for joining the forum. I hope your hives go away soon.
HivesGuy
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Title: Re: I am sure I have it.
Post by: Klope62 on May 05, 2008, 07:48:19 PM
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Yes, I can agree on some major fronts. I still love life, it has never really affected me or what I do much outside of the moment on the attack. Other than the fact that I keep my fan on nearly 24/7, except during winter of course, which I still generally need to have it on to have a peaceful sleep.
A car with the blazing sun and no AC is torture, and so is having a bad cold at night (about a month ago, I had a cycle period where I was in bed, I would cough, which would exacerbate my prickles, causing me to wake up in about 15 minutes intervals), beyond that, I try to keep my stress level cool.
I guess I can say, though, that arrival of the Hives was probably next to the biggest amount of relief I received, next to finding that initial “prickly skin” topic. All before, I had all the symptoms, but I lacked any of the visible variety, maybe chill bumps at “best”. So, to actually get a sign of something that matched Cholinergic urticaria was huge for me. Now, if I just need to take that next step and see a dermatologist.
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Title: Re: I am sure I have it.
Post by: billysielu on May 06, 2008, 02:43:46 PM
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yesterday i read this and it got me worked up and set my Cholinergic Urticaria off. today it’s done the same but not so bad, i’m half sweating. which is kinda unusually good. might be related to it being unbearably hot all day.
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Title: Re: I am sure I have it.
Post by: HivesGuy on May 07, 2008, 06:36:52 PM
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Funny that you mentioned about sweating a little billysielu. As I have mentioned before, I definitely notice an increased ability to sweat on those really hot & muggy type of days. It is like the high heat & humidity “forces” the sweat out of the pores of your skin.
It is like once the sweat finds its way out, your body doesn’t have the reaction as long as the sweat keeps on coming. The only problem is once you stop sweating, it seems like you are back to square one. The next time you get hot, it is Hiveville all over again.
I kind of visualize it like this: When your body becomes hot, or excited, nervous, etc….(basically anything that would normally cause the body to sweat) then a signal is sent down your nervous system. Instead of activating a sweat release from the sweat gland, it activates your mast cells. Histamine is released which causes the itchy/stinging/red bump reaction.
But somehow when the sweat finds its way out due to the high heat, the reaction is bypassed.
That could be completely incorrect, but that is how I try to visualize it in my mind. If we could only find out why this started happening to us….
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Title: Re: I am sure I have it.
Post by: acceptor on June 09, 2008, 11:56:41 AM
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hi there
thanks for sharing your story, my hives are very new, and i dunno if i think there getting better or im just getting used to them….. i mainly get red patches and itchiness on my face and fore arms and my scalp goes off at least once a day, but i just try to remain calm..i think concentrating on something else works to some degree, i tried taking a homeopathic pill called urticaria –nothing happened and now im trying the herb tincture urtica (stinging nettle)have to wait 2 weeks though to see if it works,
you have had your for so long i will make a big prayer for you and hope that it leaves you very soon
all my luck and kindest thoughts,
mimi
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Title: New member, my story.
Post by: Amantis on January 22, 2009, 03:05:38 PM
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Well, I’m 18. The first time I had an outbreak was when I was 16 or 17, I was in a Target(store) and all of the sudden I started getting really hot and little super itchy pin pricks started popping up all over my body, mostly my torso and arms. I needless to say was freaking out because it was unbearable like torture, I wanted to rip my flesh off, and it was extremely embarrassing to be in the middle of a store. Embarrassed+hot+panic = one of the worst outbreaks I will ever have.
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So later that week I went to a dermatologist and they did blood work and looked at my skin, nothing out of the ordinary(except high cholesterol, heh). At first I was told it could be a symptom of diabetes, but they tested and I didn’t have that. So I had some unknown ailment for the most part of a year and a half. Eventually I got worried enough to start googling all my symptoms and I came down to Cholinergic Urticaria or Miliaria (NOT to be confused with malaria). Blah blah- at last I ‘knew’ I had Cholinergic Urticaria.
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Now I hear a lot of you talk about rashes, does it mean that I can’t have Cholinergic Urticaria if I can’t see a visible rash? There might be a rash there but I wouldn’t be able to see it as my entire body is rose red from being covered in scratch marks (I look like I just got mauled by a tiger) and little bumps.
Recently (read: this week) they have become much more frequent but slightly less intense (maybe 2-3 times a day as opposed to once a week). Could this be because I started taking a chewable multi-vitamin(think Flintstones) + a Vitaman C chewable this week? I’m also thinking about getting a moisture wicking shirt, I heard that can help.
PS. All the bolds and indentations are to make this easier on the eyes to read, I pressed preview and it looked like a boring gray wall of text.
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Title: Re: New member, my story.
Post by: HivesGuy on January 22, 2009, 04:09:45 PM
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Hello Amantis,
Excellent Post and Welcome to the forum!
I can totally relate to the experiences you mentions. Just like you said, Embarrassment + panic +heat= extreme torture!! I has happened to me too more times than I care to remember.
I thought it was interesting how they suspected it could have been related to diabetes. I have read a few things online in the past, and wondered if somehow I had some blood sugar problem or something. However, my wife didn’t think so, and since you actually had a test for it, now I feel like I can say that it probably for sure has nothing to do with it (for me anyways).
About the rashes–Rash isn’t probably the best word to describe what happens to me. I made a post a few months ago and did some pictures of myself during a really bad reaction. You can find the post and the pictures at the URL below:
Basically, I just feel the itching and prickly sensation most of the time. If I get a really bad reaction (like your Target reaction), my skin gets red (both from scratching and the increased blood flow/histamine in my skin). It mostly happens on my chest and a little on my face. It isn’t really that noticeable as you can tell in the pictures. Some of the redness on my chest is from scratching.
In the last picture, I hav very light pinpoint dots that showed up for a minute or two. They are very hard to notice, and I really didn’t pay attention or notice them until I really started looking during my bad reactions. As I said, they go away in a couple of minutes leaving no trace. Some people on here get really red dots, but don’t itch as bad. Some don’t really notice them at all. I myself only get those when I have an extreme reaction.
The dots (hives) themselves are very small–take a ball point pin and make a dot on your skin- that is about the size of mine. They are really random too, and I am not usually covered in them. It is just a few here and there, and then they disappear.
As far as your question on the vitamin chewables, it may or may not be related. One thing I can say for sure is that my hives seem to come and go in intensity. Some days I can get really reactive from doing almost anything. Other days I can jump around and do physical activity for while before breaking out.
So I hope that gives you a little more info. Thanks again for the great post, and welcome to the forum.
P.S.- It is funny that you mentioned Target. I actually was working there when my hives came back. The stress of working in retail and handling the hives was way too much. I started having reactions in the middle of doing my job in front of everyone.
Plus I really hated working for that company. It was such a relief to quit (both for my hives and my sanity). lol
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Title: Re: New member, my story.
Post by: Amantis on January 22, 2009, 04:54:07 PM
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Exactly like mine! One thing I forgot to mention is the reason its so embarrassing mostly is how do you think I look itching like that? I bet people think I’m a dirty flea/lice ridden teenager with leprosy or something. :'(
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Title: Re: New member, my story.
Post by: HivesGuy on January 23, 2009, 09:25:50 AM
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Quote from: Amantis on January 22, 2009, 04:54:07 PM
Exactly like mine! One thing I forgot to mention is the reason its so embarrassing mostly is how do you think I look itching like that? I bet people think I’m a dirty flea/lice ridden teenager with leprosy or something. :'(
LOL- I feel the same way. I hate breaking out in public because I feel like people think I am some freak or crazy person or something lol. They have no idea the torture we feel when going through this.
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Title: Re: New member, my story.
Post by: billysielu on January 23, 2009, 02:46:33 PM
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My Cholinergic Urticaria used to be very visible, it looked just like Measles. Now it’s barely visible at all, although if I scratch a lot – all the scratched areas will be bright red.
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Title: Miliaria, Prickly Heat, and Other Diseases that Mimic Cholinergic Urticaria
Post by: NaKeD on September 10, 2009, 10:18:32 PM
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Hi all,
This is my first post on this forum as I happen to stumble across it while doing my usual investigation to find a cure for my ‘medical condition’ as I call it, before finding out the correct term for it (Cholinergic Urticaria).
I am grateful for this forum as every post I read I can actually relate to and not feel like a strange weird person who possibly is telling lies to everyone about how he get itchy when he tries to sweat.
I started experiencing Cholinergic Urticaria when I was 17 years old during my high school years at roughly the same time as my exams. For this I believe Cholinergic Urticaria is triggered from high level of stress (IMO). It started off as a mild irritating itch, as years go by the itch increases until I can’t stand it anymore before seeking medical profession. I visited 3 different GP all recommending moisturising cream for dry itchy skin, which didn’t help at all.
After a visit to a dermatologist I was diagnose with milaria, prickly heat or heat rash. I was given some oral medicine (natural ingredients) and heaps of cream to apply after every shower. This help reduce the itchiness by 50% but it wasn’t sufficient for me to have a normal life. Mind you the medicine cost a fortune and I needed regular visits to the doctor.
A couple of days ago just after my 24th birthday I decided to take antihistamine and to my surprise it help reduce the itch by up to 80% and it cost 1/10 of the price I use to pay from the dermatologist. I’m taking 180mg of fexofenadine hydrochloride per day, is this the best antihistamine or is there one better? I just can’t believe the lack of knowledge on Cholinergic Urticaria for doctors. I guess it’s not deadly so in terms of the level of importance it would be near the bottom.
I know one day someone out there will find a cure for it, for the time being I can finally have meetings with clients and still stay professional.
You will be seeing me around…
PS. Is there anyone else from Australia?
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Title: Re: Cholinergic Urticaria, Milaria, Prickly heat…. new member
Post by: HivesGuy on September 14, 2009, 06:21:35 AM
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Hello NaKeD,
Excellent post & welcome to the forum.
I know exactly how you feel about feeling like a “weirdo” and like you were the only person on the planet with this. I think all of us have felt like that until we realized we weren’t alone in this condition.
As far as the antihistamine questions, I recommend you try different ones. A lot of people take Zyrtec (centrizine), and have decent results. Some take claritin, some take hydroxyzine, some take what you are taking, etc. I would just try the ones you can (always follow the directions or docs orders), and stick with what works.
Unfortunately, they don’t work too well for me, so I don’t really take them often at all (if ever). But some people can manage their Cholinergic Urticaria a great deal with them.
I am definitely optimistic that we will find a “cure” and better ways to manage this over time.
Thanks again for the great post, and welcome to the forum. Let us know if anything changes, or if you find anything new out. Also, I think I do recall a few Austrailians on here (I live in the US), so you may be able to spot them eventually.
Thanks again,
Hivesguy
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Title: Re: Cholinergic Urticaria, Milaria, Prickly heat…. new member
Post by: Castvania on October 22, 2009, 10:54:52 AM
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Hey Naked, i know this post is roughly a month old but im an Aussie in Melbourne
Personally ive only ever tried the telfast 180mg tablets, they seem to reduce the severity of the itch. I find if i take a tablet before bed i dont wake up in the middle of the night with an itchy back
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Title: Re: Cholinergic Urticaria, Milaria, Prickly heat…. new member
Post by: jamesmacin on October 30, 2009, 08:23:00 AM
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Quote from: NaKeD on September 10, 2009, 10:18:32 PM
get itchy when he tries to sweat.
Initially when my Cholinergic Urticaria started only as a 24/7 itch 4 years ago, I was not sweating at all no matter what. But sweating is a normal body reaction and it is a must no matter if you happen to be a person who sweat very little under normal circumstances.
Are you sweating normally now?
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Cholinergic Urticaria is triggered from high level of stress
Yes, true, but not applicable to all the people.
Quote
fexofenadine hydrochloride , is this the best antihistamine or is there one better? I just can’t believe the lack of knowledge on Cholinergic Urticaria for doctors. I guess it’s not deadly so in terms of the level of importance it would be near the bottom.
There are so many anti-histamines on the market, but please use the one that makes you feel better for a longer period and try getting off it very now and then just to see how you cope without it.
Doctors particularly dermatologists hardly know about Cholinergic Urticaria, strange, but true.
Good luck and keep us updated about what pills help you with the itch, mine is also the same problem ie itch 24/7.
Thanks a lot,
James
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Title: Re: Cholinergic Urticaria, Milaria, Prickly heat…. new member
Post by: NaKeD on February 08, 2010, 06:45:44 AM
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Hi all,
It has been a while since I’ve visited this forum because I have forgotten about Cholinergic Urticaria. Yes correct I found the trigger to my Cholinergic Urticaria! ;D
Long story short, our company merged with another company so we needed a larger office space. We moved to another location with a better heating and cooling system. Our old place had a bad system where people with hay fever would complain about how itchy their eyes or nose were. It has been 8 months since the move. At first I didn’t notice the improvement, gradually the pain reduces until as of today i can officially say I’m Cholinergic Urticaria free. (Hopefully for good)
1. I would recommend people checking their heating/cooling system at their work or home. People like us with sensitive skin are more likely to react to bad system.
2. Drink plenty of water
3. Excercise regularly to keep the pores open (In Australia its our summer now and I love to sweat, I don’t need to exercise to sweat)
Please feel free to ask me any questions I will do my best to help. I feel your pain!
Kind Regards,
NaKeD
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Title: Revelation about GU and Hives
Post by: Enfade on August 05, 2010, 11:38:51 AM
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So I was just reading and looking around on the internet when I stumbled upon something interesting. We’ve heard of ideas about how “Prickly Heat”, also called Heat Rash, is related to our condition. Now, I kinda assumed I may have had a brush with this condition once or twice, but something has made me wonder about this. According to this article, prickly heat can be treated with a number of methods that deal with cleaning out the pores due to them being blocked, causing a prickly, irritating feeling. Sound familiar?
Well, I continued reading and those who have prickly heat may see little dots on the skin with “borders” of sorts; these are the sweat pores that are inflamed due to being obstructed. I noticed that I had this, even though I visited a dermatologist and he saw nothing. This struck me as odd, and since then I’ve noticed the symptoms of Cholinergic Urticaria and prickly heat are similar; perhaps they are one in the same, or closely related?
If you think about it, sweating when you have Cholinergic Urticaria eventually causes hives, though not instantly, while prickly heat is quite similar in that manner. They both cause irritation in the skin when you start to sweat due to something possibly blocking the pores, and possibly stop after you begin to sweat significantly. It is also hard to sweat with both of these conditions, and I’ve read of some “spots” that some believe to be hives caused by Cholinergic Urticaria stay for hours on the skin.
To make this even more convincing, I went to a natuopathic doctor to get electric acupuncture. I’ve researched and learned that a hormone known as acetyl-choline is linked closely to Cholinergic Urticaria, and I asked him to remove my sensitivity to that hormone, thinking that could solve my problems. It didn’t work, as I can tell now, so that is out of the question. It MUST be a sweat/pore problem, and I’m convinced that these two conditions are somewhat one in the same. I’m going to another dermatologist, so I will get out my results whenever I get treatment for my prickly heat, and hopefully something comes of it!
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Title: is there any other disease similar to cholinergic urticaria?
Post by: tiredofthis on May 27, 2011, 04:00:28 PM
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well, i went to the doctor (internista in spanish, don´t know how to spell it in english) anyway, he told me to make me blood test, and what happened is that everything is perfect just a little elevated meat proteins, but he told me i have the immunoglobulin low (20/100) instead of high, and he said that every allergy or kind of disease with the same patterns have that substance higher that 100..what happens? does it means that i don’t have urticaria and is something else?
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Title: Re: is there any other disease similar to cholinergic urticaria?
Post by: HivesGuy on May 27, 2011, 04:31:08 PM
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If you get hives, then you have urticaria. More specifically, if you get hives from heat/exercise/emotions, then it is possible you have cholinergic urticaria. I know of no other diseases like Cholinergic Urticaria, other than miliaria (clogged sweat pores), and exercise induced anaphylaxis/urticaria (hives only from direct active heating only).
It doesn’t matter what your immunoglobulin levels are to my knowledge in determining urticaria. All that matters is if you actually have urticaria present on your body for a diagnosis.
If the doctor was talking about allergies, then cholinergic urticaria isn’t really a typical allergy as far as we know. It is more like an autoimmune thing to our sweat or some antigen/protein in the sweat in my opinion.
If you have a large number of abnormal meat protein, maybe you lack some enzyme or something to break it down. There are a ton of these types of disorders where people may lack a certain enzyme to break something down (examples like lactose intolerance, fabry’s disease, etc).
But if your doctor isn’t familiar with Cholinergic Urticaria (and many aren’t), and you feel like your symptoms match it, then maybe you should get a second medical opinion. Most blood tests and other tests reveal almost nothing about Cholinergic Urticaria. Many people here have had a lot of these types of tests and many times they come back showing nothing abnormal.
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Title: Differences between Cholingeric Urticaria and Miliaria Profunda?
Post by: MikeC on March 26, 2012, 03:27:41 PM
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Hives Guy and Everyone is this community,
Do you guys know the key differences between Cholingeric Urticaria and Miliaria Profunda?
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Title: Re: Differences between Cholingeric Urticaria and Miliaria Profunda?
Post by: HivesGuy on April 05, 2012, 11:06:53 AM
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Hey Mike,
Miliaria is similar to Cholinergic Urticaria, but there are differences.
In miliaria profunda, there are usually very small rash that forms on the top of the skin. This is from sweat gland obstruction, which is often caused by bacteria or exposure to prolonged sweating. The rash often remains throughout the day.
As far as I know, this condition is usually self limiting, and rarely becomes a chronic problem. Also, I know that many miliaria conditions can be improved with the use of antibiotics, but I’m not sure about this one specifically. According to some sources, the feeling of pins and needles may last for a long time (or even occur hours after activity), as opposed to Cholinergic Urticaria which only happens during the moment of heat increase, and typically disappears within minutes of the exposure being removed.
With Cholinergic Urticaria, acetylcholine seems to be involved in most cases, and there is little evidence that bacteria have any signficant involvement at all (ie, antibiotics do not help).
In my mind, Cholinergic Urticaria is more of an allergic response scenario, whereas miliaria is more of a blockage due to poral occlusion problem.
Again, they are very similar in some ways, but there are some important differences.
Clinton says
Umm.. ok so unlike you all who said this whole horrible nightmare started at like 15-16 or so. Mine unfortunately started when I was 12 going 13. I’m currently 15. And at the time I had no clue whatsoever what was happening. I thought at first I had prickly heat. But I realized last month that I had C U. All this time wasted on antibiotics and all that extraneous stuff was draining. I honestly don’t know what to do other than try the things that were stated on this website. And also I just want to say I’m grateful for all who have commented, and for the person who created this magnificent website. I just wish and pray for a cure.
Hivesguy says
Clinton,
I’m sorry to hear that you’ve had this since you were only 12 years old. That’s definitely young. It didn’t hit me until I was 18 years old. However, some people on this forum have reported their young children (toddler and infant age) of having this. So it definitely can strike at any age.
I know it’s extremely hard dealing with this, but I have confidence that you’ll be able to find ways to eventually beat it.
I’m glad you found this website, and I’m glad you’ve enjoyed it thus far. What truly makes this site great is people like you (and others) who have taken the time to share their experiences and input.
Keep us all posted on how things progress. Feel free to search the site. If you have any questions you didn’t see addressed on the site, don’t hesitate to ask in the forum section.
God bless,
Ben (Hivesguy)
Cheescake says
Hi, I’m also suffering from CU since 16, now 28.
My thoughts: it actually makes sense that the urticaria would come from clogged pores if you think about it. You get a rash with elevated part of your skin, like from nettles. This makes your skin kinda “wrinkled” which increases the skin surface which consequently increases heat dissipation. So my guess is this is your body trying to loose the extra heat because the usually present sweat is not on the skin to cool it down, so it creates more skin surface.
Btw I don’t know how it is with you guys, but i get these nettle like bumps all over my body, as well as the small fluid filled pockets like in the following pic, but not as many (i hope we are allowed to post links):
http://images.medicinenet.com/images/slideshow/heat-rash-s5-photo-of-miliaria-crystalline.jpg
But these fluid bumps I only get on areas where I actually do not sweat (arms, legs)
So the idea would be to find out how to unclog the pores to sweat normally and what really causes the clogging.
Cheers
Hivesguy says
Thanks for your comment. It’s interesting that you get these small fluid-filled pouches. I never got them myself. I wonder if doctors would classify you as having cholinergic urticaria, miliaria, or both? If memory serves me right, I was under the impression that the fuild-filled pouch thing was more a sign of a type of miliaria.