A bit of background on my Cholinergic urticaria. I was diagnosed in 2003. After trial and error, I was successfully treating my cholinergic urticaria with doxepin. The doxpepin began causing me to have problems with depression, so I was switched over to a new medicine. I now take Cholchicine and it works well.
First question: Does anyone have family members with cholinergic urticaria? My 4-year-0ld daughter has always gotten red and flushed when she’s gotten too heated. About a month and a half ago, she had been out playing for awhile and was getting overheated. She ended up breaking out into hives. I got her in and cooled and they went away. She gets hot while sleeping, always has. She woke up the next morning covered in hives head to toe. I took her in to her pediatrician that morning. She was diagnosed with heat hives and prescribed a combo of Claritin and Zantac. It’s working for her.
Second question: Has anyone had high levels of Tryptase? About 3 weeks ago, I went in to my Allergist for my Cholchicine refills. While I was there, I told my doctor about my daughter and asked if CU could be hereditary. He said it was entirely possible but he knew of no definitive evidence that it is. He wanted to try to investigate that further and ordered blood work to test my Tryptase levels. My baseline Tryptase level is 18. Normal is less than 11. He said I should be fine going forward, but I could be more prone to have anaphylactic events if I were to have an allergic reaction to something.
So, I was just curious if any of you had family with cholinergic urticaria or high levels of Tryptase.