I am using Zyrtec antihistamine which contains Cetirizine, which according to Wikipedia is a key ingredient to fight cholinergic urticaria. I’ve only been on it for a few days, but it seems to have helped immensely.
Sometimes now I will get the “goosebumps” and my hair will stand on end but there will be no (or very little) accompanying pain. Relief starts to take effect about an hour after taking the pill and lasts for 12-24 hours (it’s a 24 hour pill). So far this pill had been a life saver as I don’t know how one could live like this without relief.
I had cholinergic urticaria when I was younger – in my 20’s, and it suddenly came back on (I am now 40). I believe the use of Adderall is what caused it’s return.
Anyway, my symptoms are of course when I get hot I feel like I am being stung by bees all over my arms, head, chest, back, etc. My hair stands on end and I get goosebumps until I can rapidly cool off then it all goes away in a matter of seconds.