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Anyone tried Rapid Desensitization for Cholinergic Urticaria?

January 8, 2009 by Hivesguy

Anyone tried Rapid Desensitization?

Post by: Struikgewas on March 10, 2012, 10:18:36 AM

This therapy seems to be very effective against severe cholinergic urticaria!

What are your thoughts and has anyone on this forum tried it?

Yours,

Wouter

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Title: Re: Anyone tried Rapid Desensitization?

Post by: MikeC on March 11, 2012, 02:51:14 AM

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wow that really seems like a good report. It is interesting that the Japanese doctors claim that we are allergic to the antigens from our sweat. Would we have to go to Japan for such treatment? Also I wonder if the patients stayed free from cholingeric Urt. Nice find!

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Title: Re: Anyone tried Rapid Desensitization?

Post by: yash on March 14, 2012, 01:06:55 AM

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Among all of the cholinergic urticaria theories I’ve read before, this one i think is the one that makes more sense… wow… allergic to the antigens of our own sweat… never thought of that one.

What I didnt understand well is what exactly those tests were based on and their overall procedure, and how this discovery can lead to a possible cure for this :S

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Title: Re: Anyone tried Rapid Desensitization?

Post by: HivesGuy on March 15, 2012, 08:00:14 AM

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It’s definitely interesing, if a person could confirm that the allergic issue is solely from sweat alone, and they could know that nothing else whatsoever was impacting it.

But if someone had a different subset of Cholinergic Urticaria, or another cause, then it would have limited impact.

Also, if the sweat was allergic due to food allergy manifesting itself in the form of sweat allergy (perhaps by some antigen building up in excess or something), then it would seem more logical to try to address that.

But I remember this has been discussed a few times on the forum I think. It is fascinating, and who knows what the future holds. Perhaps this will be viable option for some people.

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Title: Re: Anyone tried Rapid Desensitization?

Post by: Struikgewas on March 16, 2012, 08:36:17 AM

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Yes it is interesting. They suggest indeed that most of us are allergic to the antigens of our sweat.

Immunoglobulin E (igE) releases histamine when it binds with with antigens.

More and more reports suggest that omalizumab, an anti-Immunoglobulin E, works well against cholinergic urticaria. And this seems to be very logical, because omalizumab prevents this binding of immunoglobulin with antigens.

A problem is that omalizumab is very expensive. A injection costs between 500-1000 dollars/euro. (I personally find this no problem when it really works).

But this desensitization expiriment also confirms the antigen theory. I’m confinced that they are really getting closer now with finding out what ChU really is…

Let’s hope!!

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