I have been suffering from cholinergic urticaria for the last 3 months. I usually get severe prickly sensation in my back and legs after any physical exertion (walk, cycle) or temperature change (cool to warm). I work in NY city and have to switch 2 trains and a 15 min walk every day to and from work, so avoiding any physical activity is not an option.
I also have Polycythemia, but my dermatologist is convinced that it is cholinergic urticaria and not related. He started me on Zyrtec (Cetrizine) and Allegra and slowly increased the dosage over the last 2 months. I am currently taking 4 Zyrtecs at night and 1 Allegra + 4 Claritins (loratadine) in the morning so a total of 9 pills.
I have only seen marginal improvement. In fact, I feel like some times the intensity is worse than what it was when I started taking the antihistamines. Now he wants me to start the Levocetrizine (Xyzal). The doctor claims he specializes in cholinergic urticaria and I should follow the regimen.
I am not convinced it is going to work. I am fed up with this experimentation. I am also worried about taking too many antihistamines.