Hi everyone, I’m new here, and have LOTS of questions 🙂 I am a 30-year-old female, stay at home mom to two kiddos ages 1.5 & 3. I’m not really sure what is related to what, but I’ll go back to January 9 – I had my 4 wisdom teeth removed; 2 were impacted and surgically removed and 2 were just pulled out. I had just Novocaine (never had before) and was prescribed amoxicillin to prevent an infection. The surgery & recovery went great I had no issues at all. I have been a runner for 14 years never an issue at all.
I ran D2 xc/ track in college, have run one marathon and countless other races. So it was surprising when 13 days after the surgery I went for a run and broke out in hives. I ran 4 miles and the hives did not come on until about 15 minutes after my run. They started in my groin and armpits and spread from there to cover my trunk, legs and arms.
I took Benadryl and they started improving right away and they were gone within about 5 hours. My doctor advised me to try taking Claritin before working out again, so I did just that 2 days later. I ran 3 miles (30 mins) but started feeling a burning/ tingling in my feet at about 25 mins.
As soon as I stopped the treadmill the hives spread to the rest of my body, and I also had intense burning in my hands & feet and felt a strange sensation in my eyes & ears, like a tingling. My knees were extremely painful and my finger joints also swelled up so I had to take my wedding rings off (the tissue did not appear swollen, just the joints). I went to urgent care and they put me on a 5 day course of prednisone.
I also developed terrible malaise, fatigue, diarrhea and nausea in the following days which continued for 3 full weeks. My Dr ended up diagnosing me with a serum-like sickness reaction to amoxicillin and did not think I would have any further problems. She advised me not to run for a month. So a month later I started running again.
The first 4 runs went completely fine (15 mins, 20 mins, 25 mins and 30 mins). Run #5 (yesterday), I ran 30 minutes and again broke out into hives starting in my groin and armpits and spreading from there around 10-15 minutes after my run. I again took Benadryl and the hives subsided in about 3ish hours.
Today I started again with the nausea/ diarrhea but it’s not as bad as last time. My Dr now thinks I have cholinergic urticaria or possibly exercise induced anaphylaxis. She is prescribing me an epi pen, advised no exercise, and is having me see an allergist (I’m sure it will be a long wait).
Has anyone experienced cholinergic urticaria and had symptoms like mine? I thought I read that the hives usually come on within minutes of starting exercise, so why does mine not start until I’m done exercising (and only after workouts 25+ minutes long). I know no one can diagnose me here but I’m just wondering if anyone has experienced something similar or has any words of advice for me.